Capability
Oral Solid Dose CDMOs
Compare CDMOs with oral solid dose manufacturing capabilities for tablets, capsules, and modified-release products. Filter by batch size, coating technology, and regulatory approvals.
534 companies listed
Tablets and capsules are the workhorse of pharma, roughly 60% of all drug products, so "oral solid dose CDMO" returns a crowded field. The differences that matter are technical, not marketing. Your API's flow and compressibility decide the granulation route: direct compression if it behaves, wet or dry granulation if it doesn't. A shop built for high-shear wet granulation isn't automatically the right home for a moisture-sensitive compound that needs roller compaction. Then there's scale. A CDMO that runs elegant 5,000-tablet clinical batches may not hold content uniformity at two million tablets a day. Heading toward extended- or delayed-release? Confirm the coating and multiparticulate expertise before you commit. Potent compound? Check the containment band (OEB) of the suite you'd actually run in. 534 CDMOs here list oral solid dose. Filter by batch size, coating technology, and regulatory market.
About Oral Solid Dose Manufacturing
Oral solid dose (OSD) manufacturing is the highest-volume pharmaceutical manufacturing segment. Tablets and capsules account for approximately 60% of all drug products. The manufacturing process includes blending, granulation (wet or dry), compression or encapsulation, coating, and packaging. CDMOs range from small clinical-batch specialists to high-volume commercial manufacturers producing millions of units per day.
Modified-release technologies differentiate premium OSD CDMOs. Extended-release, delayed-release, and pulsatile-release formulations require specialized equipment and expertise in polymer coating, matrix systems, osmotic delivery, and multiparticulate approaches (pellets in capsules). These formulations improve patient compliance and can extend product lifecycle.
Companies (534)
UPM Pharmaceuticals
United States
UPM Pharmaceuticals is a pharmaceutical CDMO offering comprehensive services.
Oral Solid DoseSolid Dose ManufacturingFormulation Development
7bridges (the7bridges.com)
United Kingdom
7bridges (the7bridges.com) is a pharmaceutical CDMO offering comprehensive services.
Small Molecule APISmall Molecule Drug ProductOral Solid Dose
Frequently Asked Questions
What granulation methods do OSD CDMOs use?+
The three main approaches are: wet granulation (high-shear mixer granulation or fluid-bed granulation -- best for improving flow and compressibility), dry granulation (roller compaction -- suitable for moisture-sensitive or heat-sensitive APIs), and direct compression (simplest, for APIs with inherently good flow and compressibility). The choice depends on API properties, formulation requirements, and manufacturing efficiency goals.
What modified-release technologies are available?+
CDMOs may offer: matrix tablets (hydrophilic polymer matrices for extended release), osmotic systems (OROS-type controlled release), enteric coating (delayed release for pH-sensitive drugs), multiparticulate systems (coated pellets/beads in capsules for flexible dosing), and multi-layer tablets (for combination products or staged release). Each technology requires specialized formulation science and manufacturing equipment.
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